Timothy Eberlein

Timothy J. Eberlein, MD

  • Bixby Professor/Chairman, Department of Surgery
  • Spencer T. and Ann W. Olin Distinguished Professor
  • Director, The Alvin J. Siteman Cancer Center

Medical School

University of Pittsburgh, Pittsburgh, Pennsylvania, 1977

Post Doctoral Education

Residency: Surgery, Brigham & Women's Hospital, Boston, Massachusetts, 1984

Fellowship: Surgery Branch, National Cancer Institute.

M.A. (Hon.): Harvard University, Cambridge, Massachusetts, 1996

Board Certifications

General Surgery--Certified
Recertified 2007

Honors and Awards

2011, Honorary Member, French Academy of Surgery

2011, President, American Surgical Association

2008, Honorary Fellow, Swiss Surgical Society

2006, Sheen Award, American College of Surgeons

2004, Election to the Institute of Medicine of the National Academies of Science

2004, Longmire Lecturer – Young Surgical Investigator’s Conference, American College of Surgeons

2003, Philip S. Hench Distinguished Alumnus Award, University of Pittsburgh School of Medicine

1996, Honorary Fellow, Royal College of Physicians & Surgeons (Glasgow)

Clinical Interests

Dr. Eberlein specializes in breast oncology and breast health. Other areas of clinical interest include breast cancer prevention.

Research Interests

2004-2009: NIH 5T32, Grant Number CA009621. National Institutes of Health Advanced Training in Surgical Oncology. Timothy J. Eberlein, M.D., Principal Investigator

2010-2015: NIH 1P30, Grant Number CA91842-03. Cancer Center Support Grant. Timothy J. Eberlein, M.D., Principal Investigator
Tumor immunology and immune therapies using T-cells and T-cell subpopulations
Identification of tumor-associated antigens
Co-stimulatory molecules and pathways in human solid tumors
Clinical aspects of therapy for breast cancer

Patients Seen At

Center for Advanced Medicine
Joanne Knight Breast Health Center
4921 Parkview Place, Suite F, Floor 5
St. Louis, MO 63110
(314) 362-8021
Fax: (314) 454-1898

Contact Information

Washington University School of Medicine
Department of Surgery
Section of Endocrine and Oncologic Surgery
Campus Box 8109, 660 S. Euclid Ave.
St. Louis, MO 63110
(314) 362-8086

Selected Publications

Pub Med for Timothy J. Eberlein, M.D.
Gnerlich JL, Mitchem JB, Weir JS, Sankpal NV, Kashiwagi H, Belt BA, Porembka MR, Herndon JM, Eberlein TJ, Goedegebuure P, Linehan DC. Induction of th17 cells in the tumor microenvironment improves survival in a murine model of pancreatic cancer. J Immunol. 2010 Oct 1;185(7):4063-71.

Johnston FM, Tan MC, Tan BR Jr, Porembka MR, Brunt EM, Linehan DC, Simon PO Jr, Plambeck-Suess S, Eberlein TJ, Hellstrom KE, Hellstrom I, Hawkins WG, Goedegebuure P. Circulating mesothelin protein and cellular antimesothelin immunity in patients with pancreatic cancer. Clin Cancer Res. 2009 Nov 1;15(21):6511-8.

Tan MC, Al Mushawah F, Gao F, Aft RL, Gillanders WE, Eberlein TJ, Margenthaler JA. Predictors of complete pathological response after neoadjuvant systemic therapy for breast cancer. Am J Surg. 2009 Oct;198(4):520-5.

Bharat A, Gao F, Aft RL, Gillanders WE, Eberlein TJ, Margenthaler JA. Predictors of primary breast abscesses and recurrence. World J Surg. 2009 Dec;33(12):2582-6.

Moo-Young TA, Larson JW, Belt BA, Tan MC, Hawkins WG, Eberlein TJ, Goedegebuure PS, Linehan DC. Tumor-derived TGF-beta mediates conversion of CD4+Foxp3+ regulatory T cells in a murine model of pancreas cancer. J Immunother. 2009 Jan;32(1):12-21.

Tan MC, Goedegebuure PS, Belt BA, Flaherty B, Sankpal N, Gillanders WE, Eberlein TJ, Hsieh CS, Linehan DC. Disruption of CCR5-dependent homing of regulatory T cells inhibits tumor growth in a murine model of pancreatic cancer. J Immunol. 2009 Feb 1;182(3):1746-55.

Holwitt DM, Swatske ME, Gillanders WE, Monsees BS, Gao F, Aft RL, Eberlein TJ, Margenthaler JA. Scientific Presentation Award: The combination of axillary ultrasound and ultrasound-guided biopsy is an accurate predictor of axillary stage in clinically node-negative breast cancer patients. Am J Surg. 2008 Oct;196(4):477-82.

Kuerer HM, Eberlein TJ, Pollock RE, Huschka M, Baile WF, Morrow M, Michelassi F, Singletary SE, Novotny P, Sloan J, Shanafelt TD. Career satisfaction, practice patterns and burnout among surgical oncologists: report on the quality of life of members of the Society of Surgical Oncology. Ann Surg Oncol. 2007 Nov;14(11):3043-53.

Fields RC, Jeffe DB, Trinkaus K, Zhang Q, Arthur C, Aft R, Dietz JR, Eberlein TJ, Gillanders WE, Margenthaler JA. Surgical resection of the primary tumor is associated with increased long-term survival in patients with stage IV breast cancer after controlling for site of metastasis. Ann Surg Oncol. 2007 Dec;14(12):3345-51.

Eberlein TJ. Assessing the State of Surgical Oncology: The Future Is Now. Annals of Surgical Oncology. 2006;13(11):1345-1353.

Viehl CT, Moore TT, Liyanage UK, Frey DM, Ehlers JP, Eberlein TJ, Goedegebuure PS, Linehan DC. Depletion of CD4+CD25+ regulatory T cells promotes a tumor-specific immune response in pancreas cancer-bearing mice. Annals of Surgical Oncology. 2006;13(9):1252-1258.

Liyanage UK, Goedegebuure PS, Moore TT, Viehl CT, Moo-Young TA, Larson JW, Frey DM, Ehlers JP, Eberlein TJ, Linehan DC. Increased prevalence of regulatory T cells (Treg) is induced by pancreas adenocarcinoma. Journal of Immunotherapy. 2006;29(4):414-424.

Tanaka Y, Dowdy SF, Linehan DC, Eberlein TJ, Goedegebuure PS. Induction of antigen-specific cytotoxic T lymphocytes by recombinant HIV TAT-fusion protein-pulsed human monocyte-derived dendritic cells. Journal of Immunology. 2003;170:1291-1298.

Editorial Positions

Editor-in-Chief, Journal of the American College of Surgeons

Associate Editor, Yearbook in Surgery

Associate Editor, Annals of Surgical Oncology

Editorial Board, Annals of Surgery