physician photo

Jeffrey F. Moley, MD

  • Chief, Section of Endocrine and Oncologic Surgery
  • Professor of Surgery

Medical School

Columbia University School of Medicine, 1980

Post Doctoral Education

Surgical Oncology Fellowship - Surgery Branch, National Cancer Institute, National Institutes of Health, 1982-1985

Residency - General Surgery, Yale University School of Medicine/New Haven Hospital, 1980-1988

Board Certifications

General Surgery--Certified

Honors and Awards

1997–present: “Best Doctors in America”

2010, Listed in America's Top Doctors, Castle Connolly Medical Ltd.

2005, Performance Award for Administrative Excellence, St. Louis Veteran’s Administration Medical Center

2005, 2002: Clinical Teacher of the Year Award, Washington University School of Medicine Class of 2005, Class of 2002

2004, Meritorious Achievement Award for Administrative Excellence, Saint Louis Veteran’s Administration Medical Center

Clinical Interests

Surgical oncology, endocrine surgery, thyroid surgery, minimally invasive parathyroid and adrenal surgery, soft tissue sarcoma, melanoma

Research Interests

Subcontract UCSF / NIH
National Institutes of Health, 1R21, DK59518
Principal Investigator: Moley, Jeffrey F.
Grant Title: SLC2A9, a candidate ER GLUT in normal and cancer cells
Novartis Pharmaceuticals, Basel Switzerland
Principal Investigator: Moley, Jeffrey F.
Grant Title: A phase II trial of Imatinib Mesylate (STI 571, Gleevec) in metastatic medullary thyroid carcinoma

Study Sections

Member, National Cancer Institute Initial Review Group Subcommittee I (Career Development including NCI K08s) (Dr. Robert Bird, Scientific Review Administrator) – 2003 - 2007
Expression of glucose transporters in colon cancer, sarcomas, and endocrine tumors

Genetic events in progression of medullary thyroid cancer and pheochromocytoma

Clinical trials of novel treatments for thyroid cancer

Patients Seen At

Center for Advanced Medicine
Joanne Knight Breast Health Center
4921 Parkview Place, Suite F, Floor 5
St. Louis, MO 63110
(314) 362-2280
Fax: (314) 454-5509

Contact Information

Washington University School of Medicine
Department of Surgery
Section of Endocrine and Oncologic Surgery
Campus Box 8109, 660 S. Euclid Ave.
St. Louis, MO 63110
(314) 747-0064

Selected Publications


Pub Med for Jeffrey F. Moley, M.D.
Skinner MA, Moley JF, Dilley WG, Owzar K, DeBenedetti MK, Wells SA Jr. Prophylactic thyroidectomy in multiple endocrine neoplasia type 2A. New England Journal of Medicine. 2005;353(11):1105-1113.

Jain S, Watson M, DeBenedetti M, Hiraki Y, Moley JF, Milbrandt J. Expression Profiles Provide Insights into Early Malignant Potential and Skeletal Abnormalities in Multiple Endocrine Neoplasia Type 2B Syndrome Tumors. Cancer Research. 2004;64:3907-3913.

Augustin R, Carayannopoulos MO, Dowd LO, Phay JE, Moley JF, Moley KH. Identification and characterization of human glucose transporter-like protein-9 (GLUT9): alternative splicing alters trafficking. Journal of Biological Chemistry. 2004;279(16):16229-16236.

Grigsby PW, Siegel BA, Bekker S, Clutter WE, Moley JF. Preparation of patients with thyroid cancer for 131I scintigraphy or therapy by 1-3 weeks of thyroxine discontinuation. Journal of Nuclear Medicine. 2004;45(4):567-570.

Quayle FJ, Benveniste R, DeBenedetti MK, Wells SA, Moley JF. Hereditary medullary thyroid carcinoma in patients greater than 50 years old. Surgery. 2004;136(6):1116-11121.

Lowe JB, Hurst E, Moley JF, Cornelius LA. Sentinel lymph node biopsy in patients with thin melanoma. Archives of Dermatology. 2003;139:617-621.

Brunt LM, Lairmore TC, Doherty GM, Quasebarth MA, DeBenedetti M, Moley JF. Adrenalectomy for familial pheochromocytoma in the laparoscopic era. Annals of Surgery. 2002;235(5):713 - 20; discussion 720 - 1.

Cohen MS, Phay JE, Albinson C, DeBenedetti MK, Skinner MA, Lairmore TC, Doherty GM, Balfe DM, Wells SA Jr, Moley JF. Gastrointestinal manifestations of multiple endocrine neoplasia type 2. Annals of Surgery. 2002;235(5):648-654; discussion 654-655.

Cohen M, Hussain H, Moley JF. Inhibition of medullary thyroid carcinoma cell proliferation and RET phosphorylation by tyrosine kinase inhibitors. Surgery. 2002;132:960 - 967.

Cohen MS, Arslan N, Dehdashti F, Doherty GM, Lairmore TC, Brunt LM, Moley JF. Risk of malignancy in thyroid incidentalomas identified by fluorodeoxyglucose-positron emission tomography. Surgery. 2001;130(6):941-946.

Johnson LR, Doherty GM, Lairmore TC, Moley JF, Brunt LM, Koenig J, Scott MG. Evaluation of the performance and clinical impact of a rapid intraoperative parathyroid hormone assay in conjunction with preoperative imaging and concise parathyroidectomy. Clinical Chemistry. 2001;47: 919 - 925.

Phay JE, Hussain H, Moley JF. Cloning and expression analysis of a novel member of the facilitative glucose transporter family. Genomics. 2000;66:217 - 220.

Moley JF, Wells SA. Compartment - mediated dissection for papillary thyroid cancer. Langenbeck’s Archives of Surgery. 1999;384:9 - 15.

Moley JF, Doherty GM, Brunt MB, Lairmore TC, DeBenedetti MK. Preservation of the recurrent laryngeal nerves in thyroid and parathyroid reoperations. Surgery. 1999;126:673 - 677.

Moley JF, DeBenedetti MK. Patterns of nodal metastases in palpable medullary thyroid carcinoma. Annals of Surgery. 1999;229:880 - 887.

Editorial Positions

American Journal of Clinical Oncology, Editorial Board, 2003-present

Chapters

Hall BH, Moley JF. Hyperthyroidism. In: Cameron JL (ed.). Current Surgical Therapy. St. Louis: Mosby; 2003.

Moley JF. Medullary thyroid carcinoma. Current Treatment Options in Oncology. 2003;4:339-47.

Lairmore TC, Moley JF. Endocrine pancreatic tumors. Scand J Surg. 2004;93(4):311-315.

Moley JF. Medullary Thyroid Carcinoma. In: Clark O and Duh Q (eds.). Textbook of Endocrine Surgery. Philadelphia: W.B.Saunders;2003.

Hall BH, Moley JF. Hyperthyroidism. In: Cameron JL (ed.). Current Surgical Therapy. St. Louis: Mosby; 2003.

Moley JF, Wells SA. Pituitary and Adrenal. In: Sabiston’s Textbook of Surgery 2000. Philadelphia: W.B.Saunders; 2000.